| Date | | | |
| 1650 | | A plague rages violently in Dublin. | |
| 1652 | | A high court of justice sat at Dublin, by which Sir Phelim O'Neill and others, charged with murders during the rebellion, were condemned and executed. | |
| 1655 | | Henry Cromwell made commander-in-chief in Ireland. | |
| 1658 | | Richard Cromwell appoints his brother Henry lord lieutenant of Ireland. | |
| 1659 | | Dublin Castle seized by a party of officers favourable to the Restoration. The commissioners of parliament declare for a free government. | |
| 1660 | | A golden chain, called, from its texture, the collar of SS, presented to the mayor of Dublin by Charles II., and a foot company granted to him. Twelve bishops consecrated together in St. Patrick's Church, when the sermon was preached by Dr. Jeremy Taylor, Lord Bishop elect of Down and Connor. | |
| 1661 | | A theatre erected in Orange-street, late Smock-alley, and now West Essex-street, on the spot on which the Catholic church of St. Michael and St. John's now stands. A parliament held in Dublin. | |
| 1662 | | The dissenting congregation of Eustace street formed. | |
| 1663 | | The court of claims held in the King's Inns. Colonel Blood's plot to seize Dublin Castle discovered | |
| 1665 | | The chief magistrate of the city honoured with the title of lord mayor, as in London, and £800 granted him in lieu of the foot company. Sir Dermot Bellingham first lord-mayor | |