| Date | | | |
| 1575 | | A dreadful plague, by which the city was so depopulated, that grass grew in the streets and at the church doors. The mayor and sheriffs were sworn in, and held their court at Glasmanogue; and the lord deputy Sidney kept his court at Drogheda. | |
| 1578 | | S. St. Nicholas' Church re-edified. The wall of the Castle ditch repaired by the city. Kilmainham-bridge built by Sir Henry Sidney. The mayor of Dublin prevented from going to Cullenswood on Black Monday by a storm of wind and rain, so violent that neither bowmen nor shot could go abroad. The mayor of the Pull-ring elected at the Tholsel, instead of St. Andrew's Church, as formerly. | |
| 1579 | | The records of Ireland arranged in Birmingham Tower, Dublin Castle. | |
| 1581 | | James Usher, archbishop of Armagh, born in Dublin. | |
| 1582 | | The courts of law removed from Dublin Castle to the Dominican abbey. | |
| 1583 | | Trials by combat before the lords justices in Dublin Castle, between two of the O'Connors, in which Teige McGilpatrick O'Connor cut off the head of his adversary, Connor McConnor, and presented it to the lords justices. | |
| 1586 | | The king's exchequer, then held without the eastern gate, in the place where Exchequer-street is now built, was ransacked by a party from the mountains. | |
| 1588 | | Hugh Roe O'Donnel treacherously entrapped in his own country by the lord lieutenant's orders, and brought prisoner to Dublin Castle, whence he escaped to the O'Tooles of the mountains. Sir John Perrot, on resigning the lord lieutenancy, was escorted to his seat in Carew Castle, Pembrokeshire, by a guard of young citizens of Dublin, with shot. | |
| 1591 | | Trinity College, Dublin, founded by a charter from Elizabeth, on the site of the dissolved monastery of All Hallows or All Saints, which had been given the year before by the citizens for this purpose. | |
| 1593 | | Trinity College opened for the instruction of students. | |